Phase
Condition
Diabetes Mellitus, Type 1
Diabetes Prevention
Diabetes And Hypertension
Treatment
8-hour insulin-suspension period
Ketogenic diets
6-hour insulin-suspension period
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Adults ≥ 18 years of age.
A clinical diagnosis of type 1 diabetes (T1D) for at least one year, as per theirtreating diabetes physician in agreement with the primary investigator's clinicaljudgment (confirmatory C-peptide and antibodies will not be required).
On stable, commercial closed-loop pump therapy for the past 30 days.
Stable use of continuous glucose monitor system for the past 30 days.
Cellular phone with Android OS operating system 8.1 and above or iOS11 and aboveoperating system, for data compatibility with continuous ketone monitor mobile app (SiCKM app).
Able to perform study related tasks.
Exclusion
Exclusion Criteria:
Current or ≤ 2 weeks use of sodium-glucose cotransporter-2 (SGLT2) inhibitormedication (e.g. empagliflozin).
Current use of ascorbic acid (Vitamin C) as it may impair accuracy of the sensor.
Severe hypoglycemic episode within one month of admission, defined as an event whereglucose was <4 mmol/L resulting in seizure, loss of consciousness, needing thirdparty assistance, or need to present to the emergency department.
Diabetic ketoacidosis episode requiring medical attention or intravenous insulinwithin one month.
Planned or ongoing pregnancy or breastfeeding individuals.
Any serious medical or psychiatric illness likely to interfere with ability tocomplete the trial, as per judgement of investigators.
Study Design
Study Description
Connect with a study center
Hygea Clinic
Montreal, Quebec H4A 3T2
CanadaActive - Recruiting
Not the study for you?
Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.