MIND Diet and Cognitive Function in Middle-aged and Older Adults

Last updated: May 12, 2024
Sponsor: Zhejiang University
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Dementia

Brain Function

Treatment

Control arm

Intervention arm

Clinical Study ID

NCT06417749
LL20240353
  • Ages 40-69
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

A 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary outcomes in 1200 adults aged 40-69 years.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Normal chewing function, able to eat hard foods such as nuts.

  • Willing to participate and sign an informed consent form.

  • Able to understand research procedures and adhere to them throughout the entirestudy period.

Exclusion

Exclusion Criteria:

  • Participation in or have participated in other clinical trial studies within thepast year.

  • Medication to treat Alzheimer's or Parkinson's disease.

  • Diagnosis of severe chronic diseases, such as cancer.

Study Design

Total Participants: 1200
Treatment Group(s): 2
Primary Treatment: Control arm
Phase:
Study Start date:
May 10, 2024
Estimated Completion Date:
October 10, 2025

Study Description

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet and Cognitive Decline in Middle-aged and Elderly People is a 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary outcomes in 1200 adults aged 40-69 years. The proposed MIND diet for this study is a hybrid of the Mediterranean and DASH diets but with selected modifications based on the most compelling evidence in the diet-dementia field and Chinese Dietary Guidelines 2022. Specifically, the proposed MIND diet education will emphasize the consumption of whole grains, dark green leafy vegetables, dark red/yellow vegetables, other vegetables, berries and citrus, poultry, fish and seafood, beans and legumes, nuts, olive and seed oils, and green tea, and restrict red and processed meats, animal fat, fried foods, and sweets and pastries. The trial will employ a cluster randomization design comparing the effects on cognitive change of the MIND intervention diet education among 1200 adults aged 40-69 years. Secondary outcomes will include dietary behavior changes, health status changes, etc. The proposed study is sited at Taian, Shandong, China.

Connect with a study center

  • Mutiple Counties

    Taian, Shandong 271000
    China

    Site Not Available

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