Tapse/Pasp General Anesthesia

Last updated: July 29, 2024
Sponsor: Aydin Adnan Menderes University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Circulation Disorders

Dizzy/fainting Spells

Vascular Diseases

Treatment

HYPOTENSİON

Clinical Study ID

NCT06414811
2024-44
  • Ages 18-75
  • All Genders

Study Summary

TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.

This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Written informed consent;

  2. 18-75 years old

  3. ASA Physical Status 1-3;

  4. Patients planned for surgery

Exclusion

Exclusion Criteria:

  1. The patient is pregnant

  2. After cardiac surgery

  3. Severe pulmonary hypertension

  4. Severe valve disease

  5. Hypertrophic or dilated cardiomyopathy

  6. Presence of acute myocardial infarction

  7. Patients with severe visual or hearing impairment/disability

  8. ASA physical status IV or V

  9. Ischemic heart disease, conduction disorder.

Study Design

Total Participants: 52
Treatment Group(s): 1
Primary Treatment: HYPOTENSİON
Phase:
Study Start date:
May 15, 2024
Estimated Completion Date:
March 15, 2025

Study Description

TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection.

This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.

Patients will be measured by transthoracic echocardiography in the preoperative period, 15-30 minutes before induction.

Basal hemodynamic parameters and non-invasive and/or hemodynamic values will be recorded every two minutes after induction until surgical incision.Patients with a 30% decrease in SBP from the baseline and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered to have hypotension. Patients will be divided into 2 groups: 'with' and 'without' hypotension.

Connect with a study center

  • Ferdi Gülaştı

    Aydın, 09020
    Turkey

    Active - Recruiting

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