Rehydration Efficiency During Ad-libitum Fluid Intake

Phase

N/A

Condition

Low Blood Pressure (Hypotension)

Treatment

Liquid IV Hydration Multiplier

Plain Water

Liquid IV Sugar Free

Clinical Study ID

NCT06414291

FP00039672

Ages 18-60
All Genders
Accepts Healthy Volunteers

Study Summary

It is well established that rehydration with a carbohydrate-electrolyte solution is more effective in comparison to plain water. This is primarily based on the sodium-glucose co transporter, based on which the world health organization has based its oral rehydration solution recommendations. Also, rehydration with a solution that includes sodium and glucose plasma osmolality should not drop as much as it happens during rehydration with water. As a result, we should have higher fluid intake due to higher thirst perception and lower urinary output due to higher levels of vasopressin.

The present study aims to examine the effectiveness of a electrolyte-glucose drink on rehydration following exercise-induced dehydration.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Age 18-60 years
Training at least 2 times per week
stable weight for the last 2 months (fluctuation less than 5 pounds)

Exclusion

Exclusion Criteria:

Night shifting work
Thyroid medication
Bariatric surgery
Cardiovascular disease
Renal disease
Hepatic disease
Participating in another study at the same time
Bodyweight over 110 pounds

Study Design