Temperature Management on Postoperative Delirium

Last updated: May 12, 2024
Sponsor: Wang Hongjian
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Dementia

Treatment

3M™ Bair Hugger™ Warming Unit

Clinical Study ID

NCT06406257
2024-keyan-045
  • Ages > 65
  • All Genders

Study Summary

Presently, the effects of perioperative temperature management on postoperative delirium remain ambiguous. This study endeavors to explore the influence of intraoperative temperature variations in elderly hip fracture patients on postoperative delirium.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 65 years

  • Classified as American Society of Anesthesiologists I-III

  • Hip surgery patients who agreed to the study

Exclusion

Exclusion Criteria:

  • Non-consent to participate

  • Diagnosed neurological or psychiatric disorders including schizophrenia, epilepsy,Parkinson's disease, or myasthenia gravis

  • Coma, dementia, or language impairment affecting communication and assessment

  • History of neurosurgery

  • Use of antipsychotic medication preoperatively

  • Body temperature exceeding 38°C within 24 hours before surgery.

Study Design

Total Participants: 150
Treatment Group(s): 1
Primary Treatment: 3M™ Bair Hugger™ Warming Unit
Phase:
Study Start date:
May 20, 2024
Estimated Completion Date:
May 01, 2025

Study Description

At present, the pathophysiological mechanisms contributing to postoperative delirium in elderly hip fracture patients remain elusive, with predominant research concentrating on neural inflammation, neurotransmitter dysregulation, and metabolic irregularities. The influence of perioperative temperature management on postoperative delirium remains uncertain and may correlate with surgical modality and intraoperative temperature modulation. Hence, this study endeavors to juxtapose intraoperative temperature variations among elderly hip fracture patients, probing their ramifications on postoperative delirium.