The Effects of External Nasal Dilator Strips on Sleep and Cardiovascular Health

Last updated: June 18, 2025
Sponsor: Florida State University
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

External Nasal Dilator Strip

Clinical Study ID

NCT06403098
STUDY00004863
  • Ages 18-30
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The goal of this interventional study is to learn if wearing an external nasal dilator strip while sleeping changes objective and perceived sleep quality, immediate post-waking blood pressure, and immediate-post waking heart rate variability.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18-30

  • BMI <30

  • Has a smartphone and is willing to download EliteHRV and OMRON mobile applications.

  • Able to use a nasal dilator strip

Exclusion

Exclusion Criteria:

  • Overt cardiovascular (e.g., diagnosed hypertension), respiratory, neurological,renal, liver, and/or metabolic health conditions.

  • Current or recent (regular use within the past 6 months) use of tobacco or nicotineproducts (e.g., cigarettes).

  • Currently pregnant, trying to become pregnant, or lactating.

  • Inability to breathe through the nose.

Study Design

Total Participants: 30
Treatment Group(s): 1
Primary Treatment: External Nasal Dilator Strip
Phase:
Study Start date:
May 02, 2024
Estimated Completion Date:
June 16, 2025

Study Description

Nasal dilator strips are strips often made up of stiff plastic, placed on the lower bridge of the nose by an adhesive strip. They work by slightly pulling the nostrils and surrounding nose bridge area outward, dilating the nostrils, and decreasing air resistance. Nasal breathing is associated with lower diastolic blood pressure, an important marker of heart health, in comparison to mouth breathing. In addition to blood pressure, nasal breathing during sleep is potentially related with better sleep quality. Participating in this study will help us understand the effect nasal dilator strips have on cardiovascular and sleep health. Better understanding of the benefits of nasal dilator strips will provide important knowledge to researchers who study how the body works.

Connect with a study center

  • Cardiovascular and Applied Physiology Laboratory

    Tallahassee, Florida 32306
    United States

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.