Phase
Condition
Vascular Diseases
Chest Pain
Hypercholesterolemia
Treatment
Coronary artery bypass grafting
Percutaneous coronary intervention
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Patient must identify as Black race or Hispanic ethnicity
Patient is at least 18 years old.
Multivessel or left main CAD is present for which revascularization is intended andfor which there is equipoise between CABG and PCI according to local Heart Teamassessment.
Ability to provide written informed consent and comply with all follow-upprocedures, including QOL questionnaires.
Exclusion
Exclusion Criteria:
ST-segment elevation MI within 3 days
Cardiogenic shock
Prior PCI within 1 year or any prior CABG anytime
Planned hybrid revascularization (PCI after CABG or CABG after PCI)
Planned single vessel revascularization (other than isolated left main disease)
Need for any cardiac surgical or interventional procedure other than coronaryrevascularization at the present time or anticipated within 3 years, with theexception that surgical or interventional left atrial appendage ligation orocclusion and/or atrial fibrillation ablation may be performed at site discretioneither during or subsequent to the index revascularization procedure
Pregnancy (women of child-bearing potential must have a negative pregnancy testwithin 1 week before randomization) or intent to become pregnant within 1 year afterrandomization
Unable to tolerate, obtain or comply with dual antiplatelet therapy for at least 3months if presentation with stable CAD or 6 months if presentation with atroponin-positive acute coronary syndrome
Current participation in another investigational drug or device study that has notreached its primary endpoint
Life-expectancy less than 3 years due to concomitant non-cardiac conditions
Any condition(s) are present that are likely to interfere with the study protocolprocedures including medication adherence and follow-up through 10 years (e.g.mental disability, substance abuse, anticipated international relocation, etc.)
Study Design
Study Description
Connect with a study center
Adventist Health Glendale
Glendale, California 91206
United StatesActive - Recruiting
Emory University
Atlanta, Georgia 30322
United StatesActive - Recruiting
Ascension St. Vincent Cardiovascular Research Institute
Carmel, Indiana 46290
United StatesActive - Recruiting
Baptist Health Lexington
Lexington, Kentucky 40503
United StatesActive - Recruiting
Baptist Health Louisville
Louisville, Kentucky 40207
United StatesActive - Recruiting
Massachusetts General Hospital
Boston, Massachusetts 02114
United StatesActive - Recruiting
Englewood Hospital
Englewood, New Jersey 07631
United StatesActive - Recruiting
NewYork-Presbyterian Hospital - Queens
Flushing, New York 11355
United StatesActive - Recruiting
Columbia University Irving Medical Center/NewYork-Presbyterian Hospital
New York, New York 10032
United StatesActive - Recruiting
Icahn School of Medicine - Mount Sinai Hospital
New York, New York 10029
United StatesActive - Recruiting
Icahn School of Medicine - Mount Sinai Morningside
New York, New York 10025
United StatesActive - Recruiting
Weill Cornell Medicine/NewYork-Presbyterian Hospital
New York, New York 10065
United StatesActive - Recruiting
Westchester Medical Center
Valhalla, New York 10595
United StatesActive - Recruiting
Duke University
Durham, North Carolina 27710
United StatesActive - Recruiting
Ohio State University
Columbus, Ohio 43210
United StatesActive - Recruiting
Methodist Le Bonheur Healthcare
Memphis, Tennessee 38104
United StatesActive - Recruiting
Ascension Saint Thomas Hospital
Nashville, Tennessee 37205
United StatesActive - Recruiting
Baylor Scott and White
Dallas, Texas 75246
United StatesActive - Recruiting

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