A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live CoActive Exercise Coaching and Personalized Digital Application on Cancer Survivors' Quality of Life

Last updated: December 9, 2025
Sponsor: Complement Theory Inc.
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Non-small Cell Lung Cancer

Colon Cancer; Rectal Cancer

Colorectal Cancer

Treatment

Digital application with expert guidelines on lifestyle modification

Complement Theory's Live 1:1 Exercise Coaching and Personalized Digital Application

Complement Theory's Live CoActive Exercise Coaching and Personalized Digital Application

Clinical Study ID

NCT06397651
Pro00077693
  • Ages > 21
  • All Genders

Study Summary

A Decentralized, Double-blinded, Randomized, 18 month, Parallel-group, Superiority Study to evaluate the impact of Complement Theory's Live Coactive Exercise Coaching and Personalized Digital Application on Cancer Survivors' Quality of Life

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Cancer Type: Breast, Prostate, Colorectal, Lung and Other Cancer

  • Cancer Stage: Stage 1 to 4

  • Treatment Status: Has undergone any cancer-related treatment in last 12 months

  • Age: Above 21 years

  • Permission to access to last 1 year digital health records

  • Access to smartphone or a tablet

Exclusion

Exclusion Criteria:

  • Excludes individuals who have undergone surgery within the last 4 weeks or willundergo surgery in the next 4 weeks

  • Participants declared medically unfit by their physicians to do physical exercise

  • ECOG Score 3,4 or 5

Study Design

Total Participants: 146
Treatment Group(s): 3
Primary Treatment: Digital application with expert guidelines on lifestyle modification
Phase:
Study Start date:
May 12, 2024
Estimated Completion Date:
February 28, 2026

Study Description

The randomized controlled trial (RCT) aims to evaluate the efficacy of Complement Theory's (CT) personalized and interactive, evidence-backed lifestyle program in improving Cancer Survivors' Quality of Life across all major cancer types.

Distinct from conventional interventions, CT's program offers live CoActive coaching through a mobile app, concentrating on Exercise and Meditation, and is enriched with evidence-based advice on Diet. This trial is pivotal in assessing the program's effectiveness against an active comparator - expert-recommended lifestyle modification resources suitable for cancer survivors -- to isolate the impact of coaching and personalization.

The primary objective is to investigate whether CT's novel approach can significantly improve Quality of Life for survivors. Furthermore, the trial seeks to measure absenteeism and presenteeism at work to provide a holistic evaluation of the program's impact on patient care and well-being. As an exploratory effort, the trial will also measure changes in healthcare expenditure across all survivors along with assessing cancer progression, recurrence in Prostate, Lung and Colorectal cancer survivors.

Connect with a study center

  • Complement Theory Inc.

    Dover 4142290, Delaware 4142224 19901
    United States

    Site Not Available

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.