The Relationship Between Diaphragm Muscle Thickness and Fibromyalgia

Last updated: January 25, 2025
Sponsor: Gaziosmanpasa Research and Education Hospital
Overall Status: Completed

Phase

N/A

Condition

Fibromyalgia

Depression

Treatment

Fibromyalgia study form

Ultrasonographic Diaphragm Thickness Measurement

Pulmonary function test

Clinical Study ID

NCT06396949
97
  • Ages 18-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Fibromyalgia syndrome is characterized by chronic pain, fatigue, sleep problems and functional symptoms. Fatigue, anxiety and depression disorders, poor quality of life, sleep disorders, decreased concentration, and impaired cognitive functions are non-specific pain-related symptoms.

Various studies have reported decreased chest expansion, maximal ventilatory volume and maximal expiratory pressure in fibromyalgia patients with widespread body pain. Additionally, dyspnea is a symptom associated with respiratory muscle weakness and is associated with general fatigue. In these individuals, lower data are obtained in daily living activities and general health evaluation surveys. We did not find any study in the literature regarding the relationship between diaphragm thickness and fibromyalgia symptoms. In the light of these data, we aimed to evaluate the thickness of the diaphragm, one of the most important inspiratory muscles, in fibromyalgia patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients diagnosed with fibromyalgia according to the 2016 ACR (American College ofRheumatology) diagnostic criteria without any comorbidities (such as liver, kidneyfailure, DM, rheumatic disease)

  • Patients who underwent Pulmonary Function Test (PFT)

  • Patients without pulmonary disease

  • 18 -50 years old women and men

Exclusion

Exclusion Criteria:

  • Congenital spinal, costal and diaphragmatic anomalies neuromuscular disease

  • Respiratory system diseases that affect lung functions

  • Patients who cannot cooperate with spirometry.

  • Having surgery to the chest wall or spine

  • Those with BMI > 25

  • Those with liver, kidney failure, DM, rheumatic disease, neurological disease

  • Individuals < 18 years and > 50 years old

Study Design

Total Participants: 45
Treatment Group(s): 3
Primary Treatment: Fibromyalgia study form
Phase:
Study Start date:
December 15, 2023
Estimated Completion Date:
May 30, 2024

Study Description

Demographic information of all individuals included in the study will be collected. Daily living activity will be evaluated with Short Form-36 (SF-36), Fibromyalgia Impact Questionnaire (FIQ), Pittsburgh Sleep Quality Questionnaire (PSQI) and Beck Depression Inventory. In order to evaluate the respiratory function test in both the fibromyalgia and control groups, three consecutive measurements will be taken with a hand spirometer and the arithmetic average of these three measurements will be recorded. In fibromyalgia and control patients, diaphragm thickness was measured at 8-9 degrees on the right anterior axillary line with a 6-14 Mhz linear, conventional ultrasound probe (Mindray DC-8, Shenzen Mindray Bio-Medical Electronics CO. LTD., P.R. China) in the supine position. It will be measured at the end of inspiration and expiration from the intercostal space. Three measurements will be made and the arithmetic average will be evaluated.

Connect with a study center

  • Deniz Oke

    Istanbul, Gaziosmanpasa 34255
    Turkey

    Site Not Available

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