Phase
Condition
Amyotrophic Lateral Sclerosis (Als)
Pseudobulbar Affect
Myasthenia Gravis (Chronic Weakness)
Treatment
Resting State Magnetoencephalography
Diffusion Kurtosis Imaging (DKI)
Clinical Study ID
Ages 18-90 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Diagnosed with ALS in the last 6 months according to Gold Coast Criteria
Exclusion
Exclusion Criteria:
Lack of ability to answer survey through own ability or through a surrogate,for example by hand controlled, eye-controlled computer and/or tablet, orthrough telephone interview.
Lack of ability to cooperate.
Pregnancy
Drug addiction defined as the non-prescribed use of cannabis, opioids, or othernarcotics.
Alcohol addiction defined as over 21 units weekly.
Lesional neurological diseases, such as stroke, tumor or multiple sclerosis
Epilepsy
Neurodegenerative diseases other than ALS
Severe psychiatric disease such as major depression disorder, bipolar disease orschizophrenia
Contraindication for MRI and MEG scan according to hospital guidelines
Severe liver or kidney disease
Dysregulated heart disease
Ongoing treatment with any antidepressants or any antipsychotics at recruitment.
Diagnosed with frontotemporal dementia.
Study Design
Connect with a study center
Aalborg University hospital
Aalborg, Northern Jutland 9500
DenmarkActive - Recruiting
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