Idiopathic Generalized Epilepsy Syndromes

Phase

N/A

Condition

Epilepsy

Seizure Disorders

Treatment

N/A

Clinical Study ID

NCT06388174

S2022-0336

Ages 4-40
All Genders

Study Summary

The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance.

According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patients are consecutively and prospectively enrolled from epilepsy center, withnewly diagnosed epilepsy or established epilepsy.
Patients have a diagnosis of idiopathic generalized epilepsy (IGE), according to the 2022 diagnostic criteria.
Comprehensive clinical information is collected, and 24 hourvideo-electroencephalography is performed.
Sign the informed consent forms.

Exclusion

Exclusion Criteria:

Other epilepsy syndromes are considered during follow-up, such as geneticgeneralized epilepsy.
Lost to follow-up

Study Design

January 01, 2023

December 31, 2033

Study Description

the Long-term prognosis include the rate of drug-resistent epilepsy, relapse after drug withdrawn, common comorbidities such as mood disorders, attention deficit hyperactivity disorder (ADHD) and learning disabilities.

Connect with a study center

2nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang 310000
China
Site Not Available
2nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou 1808926, Zhejiang 1784764 310000
China
Active - Recruiting

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