Last updated: May 6, 2024
Sponsor: University of British Columbia
Overall Status: Active - Recruiting
Phase
N/A
Condition
Diabetes Mellitus, Type 2
Diabetes Prevention
Diabetes And Hypertension
Treatment
Exercise snacks
Clinical Study ID
NCT06382246
H24-Acute-ExSnacks
Ages 30-75 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Aged 30-75 years old.
- Have physician-diagnosed type 2 diabetes.
- Currently participating in less than 150 minutes of moderate-to-vigorous intensityaerobic exercise per week.
- Have a body mass index between 18.5 and 40 kg/m2.
- Have had a stable medication dosage and no changes to the number of prescribedmedications for at least 6 months.
- Able to maintain current medication doses during the study.
- Able to maintain current physical activity patterns during the study.
- HbA1c is less than or equal to 8.5%.
- Have access to a computer, tablet, or smartphone for intervention delivery andtracking.
- Can travel to McMaster University for in-person laboratory testing visits.
- Can read, write, and understand English.
- Anticipate having access to the internet for the duration of the intervention (i.e.,over the next 3-4 months).
- Cleared for exercise participation based on the CSEP Get Active Questionnaire and theRose Angina Questionnaire.
Exclusion
Exclusion Criteria:
- Taking 4 or more glucose-lowering medications.
- Taking insulin.
- Taking beta-blockers.
- Taking 3 or more commonly prescribed medications for the prevention of cardiovasculardisease (e.g., statins, antihypertensives).
- Have had an episode of severe hypoglycemia in the past 6 months (defined as havingneurological symptoms consistent with neuroglycopenia and required assistance intreatment by a second party).
- Currently a cigarette smoker.
- Have a chronic musculoskeletal condition that would prevent participation in exercise.
- Have had a recent (within the last 2 years) cardiovascular event that preventsparticipation in exercise.
- Experience angina upon exertion.
- Have uncontrolled high blood pressure (hypertension) or an atypical blood pressure orpulse rate at rest or during exercise as determined by a physician.
- Have a scheduled surgical procedure within the next 3-4 months that would preventexercise participation.
- Currently diagnosed with a cardiac or pulmonary disease (e.g., angina, arrythmia,exercise-induced bronchospasm) that would prevent exercise participation.
- Have a psychiatric disorder that could prevent you from completing the studyprocedures or visits.
- Have donated more than 0.5 L of blood within the last 4 weeks.
- Currently following an extreme diet (e.g., very low carbohydrate/calorie, ketogenic)or taking dietary/nutritional supplements that impact glucose control (e.g., exogenousketones).
- Currently have diabetic ulcers, peripheral vascular disease, or diabetic neuropathythat will prevent participation in exercise.
- Currently on dialysis.
- Currently participating in another clinical trial that interferes with the studyprocedures.
- Currently pregnant or planning on becoming pregnant during the intervention (i.e.,within the next 3-4 months).
Study Design
Total Participants: 30
Treatment Group(s): 1
Primary Treatment: Exercise snacks
Phase:
Study Start date:
April 20, 2024
Estimated Completion Date:
July 15, 2025
Study Description
Connect with a study center
University of British Columbia Okanagan
Kelowna, British Columbia V1V 3G1
CanadaActive - Recruiting
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