DPP Feasibility Study of Breastfeeding - eMOMS 2.0

Last updated: December 17, 2025
Sponsor: University of Kansas Medical Center
Overall Status: Completed

Phase

N/A

Condition

Pregnancy

Breast Feeding

Obesity

Treatment

Usual Care

Breastfeeding

Diabetes Prevention Program

Clinical Study ID

NCT06372860
RKS2018350
3P20GM144269-02S2
  • Ages > 18
  • Female

Study Summary

The purpose of this study is to investigate the impact of a comprehensive intervention that combines breastfeeding support with a diabetes prevention-based program (DPP) on postpartum weight retention and lactation duration among women with pre-pregnancy overweight or obesity. This intervention, named eMOMS, is delivered by a certified health coach via a mobile health (mHealth) application.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Pregnant

  • In second trimester or early third trimester

  • BMI >/= 25 and < 35

  • At least 18 years old or older

  • Able to read and understand English

  • Able to learn and use a video platform

Exclusion

Exclusion Criteria:

  • Complications related to pregnancy that require emergency care

  • Thyroid disease

  • Multiple gestation

  • Substance abuse within last 3 years

  • Assisted reproductive technology (ART)-related pregnancy

  • Current smoker

  • Prior bariatric surgery

  • In weight-loss program within 3 months of conception

  • BMI >/= 35

  • Unable to attend intervention/ follow-up visits

  • Unwilling to self-monitor data collection

  • Unable to complete intervention

  • Presence of any condition that limits walking

  • Presence of any condition that limits following diet recommendations

  • Pregnancies complicated with fetuses diagnosed with lethal malformations/conditions

Study Design

Total Participants: 43
Treatment Group(s): 3
Primary Treatment: Usual Care
Phase:
Study Start date:
April 30, 2024
Estimated Completion Date:
August 31, 2025

Study Description

This study is a randomized controlled trial designed to determine the feasibility and efficacy of a combined breastfeeding, diabetes prevention-based program (DPP) in a cohort of overweight or obese women to be followed during pregnancy through 3 months postpartum. The trial will have two study arms: DPP + breastfeeding (Tx1) and Usual Care (Tx2).

Aim 1: Quantify interest in use of the DPP-lactation mobile health (mHealth) application among target population. To accomplish this, we will: (1) measure research engagement including rates of screening, recruitment, and retention among users, especially rural and racially/ethnically diverse women; (2) assess barriers/facilitators to enrollment/retention through surveys and semi-structured in-depth interviews or focus groups; and (3) evaluate intervention uptake, delivery, and adherence via tracking/measuring use of the mHealth app.

Aim 2: Measure weight loss and duration of lactation through 3 months postpartum among target population. To accomplish this, we will measure pre-pregnancy weight, weight at study entry, weight immediately prior to and after delivery, and weight at specific postpartum time points. Lactation and infant feeding practices will be measured at similar postpartum time points.

Connect with a study center

  • Via Christi Maternal Fetal Medicine Clinic

    Wichita, Kansas 67218
    United States

    Site Not Available

  • Via Christi Maternal Fetal Medicine Clinic

    Wichita 4281730, Kansas 4273857 67218
    United States

    Site Not Available

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