Postoperative nausea and vomiting is one of the most common postoperative complications
second only to postoperative pain. Studies have reported that without any antiemetic
prevention treatment, the overall incidence of PONV in surgical operations is up to 20-30%,
and the incidence of PONV in high-risk patients such as thyroid surgery is even up to 70-80%.
The pathogenesis of postoperative nausea and vomiting is very complex, including central,
peripheral receptors and multiple nerve pathways. When peripheral receptors are stimulated,
the signal passes through the afferent nerve to the vomiting center, causing nausea and
vomiting. The emetic chemical receptors are rich in many receptors, which can directly feel
various toxins, metabolites or drugs in the blood and cerebrospinal fluid, project signals to
the nerve center and then spread to the cerebral cortex, causing nausea and vertigo, or
transmit signals along the vagus nerve, glossopharyngeal nerve, spinal nerve, etc. to the
digestive tract, diaphragm and abdominal wall muscles, resulting in the opening of the
sphincter in the upper esophagus and strong contraction of the diaphragm. Abdominal muscles
contract, so that the stomach pressure increases, stomach contents through the digestive
tract is expelled from the body, vomiting.
Thyroid, as the endocrine organ of human body, mainly secretes thyroid hormone and
participates in human metabolism. With the progress of modern medical technology, although
thyroid postoperative complications have decreased, due to the limited operating space of
thyroid surgery, in order to fully exposed the surgical field of vision and facilitate the
operation of surgeons, patients often take the cervical hyperextension position, that is,
patients take the supine position with high shoulder pads. Tilt your head back so that your
lower jaw, trachea, and sternum are at the same level, allowing the thyroid gland to protrate
forward as much as possible. Although this position is easy for surgeons to operate, due to
the complex anatomical structure around the thyroid gland, adjacent to important blood
vessels and nerves, this position often causes thyroid surgical position syndrome in
patients, that is, nausea and vomiting, dizziness, headache, tinnitus, neck radiation pain
and other symptoms, which not only increases patients' pain, but also seriously reduces
patients' medical experience.
Stellate ganglion block has been proved to be widely used in clinic and can play a positive
role in multiple organs and systems of the whole body. In clinical work, stellate ganglion
block is more widely used in the treatment of various pain, autonomic nerve disorders and
other diseases. However, there are few clinical studies on whether stellate ganglion block
can be used as an effective and feasible means to prevent postoperative nausea and vomiting
and the related mechanisms to prevent the possible occurrence of nausea and vomiting.
Therefore, this study will explore the preventive effect of stellate ganglion block on
postoperative thyroid nausea and vomiting, and hope to explore its possible mechanism, so as
to provide more effective and feasible methods for clinical prevention of postoperative
nausea and vomiting and improve patients' medical comfort and satisfaction.