ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair

Last updated: April 8, 2025
Sponsor: University Hospital, Basel, Switzerland
Overall Status: Active - Recruiting

Phase

N/A

Condition

Hernia

Pentalogy Of Cantrell

Treatment

Extended totally extraperitoneal repair

Intraperitoneal onlay mesh

Clinical Study ID

NCT06367309
2023 - 02357
  • Ages > 18
  • All Genders

Study Summary

This study investigates on the effect of two different operative techniques to treat abdominal wall hernias.

The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a better outcome than the IPOM (Intraperitoneal onlay mesh) technique.

The main questions it aims to answer are:

  • pain after the operation

  • rate of complications

  • rate of recurrence and reoperations

  • quality of life.

Participants will:

Either be operated using the eTEP or the IPOM technique. Be followed up either in person or via email / phone call at day 1, day 7, day 14, 6 weeks, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patient age >18 years

  • Informed consent obtained

  • Primary or incisional ventral hernia

  • Epigastric, umbilical or infraumbilical ventral hernias with transversal diameter >1cm and

  • If multiple hernias: cumulative transversal diameter

  • Considered eligible for minimally-invasive approach

Exclusion

Exclusion Criteria:

  • Subxyphoidal or suprapubic hernias

  • precedent hernia treatment with mesh placement in the retromuscular space

  • liver disease defined by the presence of ascites

  • end-stage renal disease requiring dialysis

  • need of an emergency surgery

  • pregnancy

  • need of rectus diastasis treatment intraoperatively

Criteria for participating surgeons

  • Each participating surgeon has performed 20 or more laparoscopic IPOM procedures and 20 or more eTEP procedures.

Study Design

Total Participants: 138
Treatment Group(s): 2
Primary Treatment: Extended totally extraperitoneal repair
Phase:
Study Start date:
July 01, 2024
Estimated Completion Date:
December 31, 2030

Connect with a study center

  • St. Clara Hospital

    Basel, Basel-Stadt 4058
    Switzerland

    Active - Recruiting

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