The Effects of Pain and Pain Relief on Peripheral Nerve Excitability

Last updated: April 9, 2024
Sponsor: University of Aarhus
Overall Status: Active - Recruiting

Phase

N/A

Condition

Pain

Treatment

Heat Stimulation

Clinical Study ID

NCT06356376
UAarhus_AGK_MNG_2
  • Ages 18-75
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study will assess changes in nerve excitability of C-fibers, and changes in sympathetic or parasympathetic tone, when the subject experiences pain and pain relief.

The investigators will continuously measure blood pressure, heart rate, respiration rate, gastric motility, sympathetic skin response and C-fiber excitability while using thermal stimuli before and after an analgesic.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Healthy Participants able to give informed consent.

Exclusion

Exclusion Criteria:

  • Chronic pain conditions
  • Neurological or Psychiatric disease
  • Other major diseases
  • Pain medication within the last 24 hours

Study Design

Total Participants: 30
Treatment Group(s): 1
Primary Treatment: Heat Stimulation
Phase:
Study Start date:
December 20, 2023
Estimated Completion Date:
April 30, 2024

Connect with a study center

  • Danish Pain Research Center

    Aarhus N, 8200
    Denmark

    Active - Recruiting

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