Pharmacy-based PrEP for Young Women Who Sell Sex in Zimbabwe

Last updated: March 29, 2024
Sponsor: University of California, Berkeley
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Pharmacy-based PrEP refill and gift voucher

Control (Standard of care)

Clinical Study ID

NCT06348069
2022-11-15783
  • Ages > 16
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Pharmacy-based PrEP for Young Women who Sell Sex in Zimbabwe is a cluster-randomized control trial and pilot study co-led by Dr. Euphemia Sibanda, Reader (Associate Professor) of Global Health and Epidemiology at Liverpool School of Tropical Medicine, UK and Research Director at the Centre for Sexual Health and HIV Research (CeSHHAR Zimbabwe) and Dr. Sandra McCoy, Professor of Epidemiology and Biostatistics at the University of California, Berkeley. The goal of the proposed study is to optimize, refine and pilot a pharmacy-based PrEP intervention for female sex workers (FSW) in Zimbabwe. Despite efforts to reach the most impacted and vulnerable populations with PrEP, retention rates, particularly among FSW in Africa, are very low. Relatively high levels of uptake indicate that FSW are interested in PrEP and ready to initiate it, but in most cases fewer than 50% of those who initiate return for medication refills by month 4. Pharmacy-based PrEP has the potential to address known barriers to PrEP retention among FSW such as stigma and access, and coupled with a small escalating incentive in the form of a gift card incentive, could also boost motivation for effective use of PrEP.

Eligibility Criteria

Inclusion

Inclusion Criteria:

    1. Exchanged sexual intercourse for money or gifts in past 6 months
    1. Age 16 or older
    1. HIV negative (via rapid test per national guidelines) at enrollment and no signs/symptoms of acute HIV infection

Study Design

Total Participants: 200
Treatment Group(s): 2
Primary Treatment: Pharmacy-based PrEP refill and gift voucher
Phase:
Study Start date:
March 25, 2024
Estimated Completion Date:
December 31, 2025

Connect with a study center

  • CESHHAR Zimbabwe

    Harare, 0000
    Zimbabwe

    Active - Recruiting

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