Last updated: March 27, 2024
Sponsor: University of Bari
Overall Status: Active - Recruiting
Phase
N/A
Condition
Lung Disease
Treatment
End-inspiratory Maneuvers
Clinical Study ID
NCT06344234
0049191
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Age greater than or equal to 18 years.
- Non-pregnant and non-lactating.
- Monitored through esophageal pressure for clinical decision before extubation.
- Able to provide written informed consent to participate in the study.
Exclusion
Exclusion Criteria:
- Patients with severe facial trauma or deformity that precludes the placement of afacemask or esophageal catheter.
- Patients with neuromuscular disorders that may impair inspiratory drive and effort.
- Patients with acute exacerbation of COPD
- Patients with esophageal or tracheal abnormalities that impede esophageal manometry.
- Patients with a known hypersensitivity or allergy to any of the materials used in thestudy.
- Excessive air leak (difference between inspiratory and expiratory tidal volume majoror equal to 10%)
Study Design
Total Participants: 60
Treatment Group(s): 1
Primary Treatment: End-inspiratory Maneuvers
Phase:
Study Start date:
November 01, 2023
Estimated Completion Date:
June 01, 2026
Connect with a study center
Azienda ospedaliero-universitaria consorziale policlinico di Bari
Bari, 70124
ItalyActive - Recruiting


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