PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)

Last updated: March 18, 2025
Sponsor: Ospedale Edoardo Bassini
Overall Status: Completed

Phase

N/A

Condition

Anesthesia (Local)

Anesthesia

Treatment

PENG + LFCN block

FIC block

Clinical Study ID

NCT06342102
ID 4286
  • Ages > 18
  • All Genders

Study Summary

Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus expediting hospital discharge. Amongst the many peripheral nerve blocks, FIB (fascia iliaca block) has been recommended as the block of choice by many international guidelines since it offers the best pain control with a relatively low risk of motor block. PENG (pericapsular nerve group) and its association with LFCN (lateral femoral cutaneous nerve) has been proposed as an effective alternative that offers comparable, If not better, pain control with a considerably lower risk for motor block compared to FIB. Given the novelty of this block, there are few published papers on the subject, mostly case series or case reports thus justifying the need for retrospective study.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • elective total hip replacement surgery for non-traumatic hip disease,

  • age over 18 years,

  • complete clinical chart including type of peripheral nerve block performed,

  • signed consent form for spinal anesthesia and peripheral nerve block.

Exclusion

Exclusion Criteria:

  • preoperative opioid therapy,

  • having received a peripheral nerve block other than PENG + LFCN or FICB,

  • having received general anesthesia,

  • incomplete chart,

  • documented muscle weakness

  • deviation from the established post-operative analgesia protocol.

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: PENG + LFCN block
Phase:
Study Start date:
March 26, 2024
Estimated Completion Date:
April 30, 2024

Study Description

The primary outcome was the degree of residual quadriceps femoris muscle paresis assessed with the MRC (medical research council) scale at 6 hours between PENG and LCFN. The secondary outcomes were NRS (numeric rating scale) at 6,12, 24 hours, total opioid consumption expressed as milligrams of morphine equivalents (MME), time to first rescue opioid and time to first postoperative ambulation.

Connect with a study center

  • ASST Nord Milano - Ospedale E. Bassini

    Cinisello Balsamo, Italy/Milano 20092
    Italy

    Site Not Available

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