Radiotherapy Treatments for Neoplasms of the Limbs

Last updated: August 22, 2025
Sponsor: European Institute of Oncology
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neoplasms

Bone Metastases

Treatment

N/A

Clinical Study ID

NCT06335251
IEO 0728
  • Ages > 18
  • All Genders

Study Summary

In this observational study patients treated at European Institute of Oncology with radiotherapy to limbs will be included

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients treated with radiotherapy for curative, palliative, neo-adjuvant, andadjuvant purposes in the upper and lower limbs for: Primary bone tumors, Primary soft tissue tumors, Primary tumors of thecardio-circulatory system, Primary tumors of the lymphatic system, Primary tumors ofthe nervous system and skin, Secondary metastases from various origins localized inthat district.

  2. Signed informed consent

Exclusion

Exclusion Criteria:

  1. Radiotherapy in districts other than limbs.

Study Design

Total Participants: 3000
Study Start date:
February 22, 2018
Estimated Completion Date:
December 31, 2025

Study Description

Approximately 60% of patients with neoplasms receive radiotherapy as part of their oncological treatment. Various primary tumors as well as metastases of various origins can be localized in the upper or lower limbs. Patients with such neoplastic localizations will therefore receive radiotherapy treatment possibly associated with other systemic or surgical treatments.

Treatment choice is usually established following multidisciplinary discussions, based on disease characteristics and stage, concurrent pathologies and pharmacological treatments, patient preferences, and functional aspects.

Data collection related to radiotherapy plays a crucial role in understanding various clinical aspects of the treatment itself. The availability of data from an increasing number of patients will allow the identification of clinical situations or technical parameters of radiotherapy correlated with treatment tolerance and effectiveness, aiming to identify the best treatment for these oncological pathologies.

This project aims to collect data related to radiotherapy treatments for primary or secondary neoplasms localized in the upper or lower limbs for scientific dissemination with the goal of establishing the basis for evaluating achieved results over time, and deriving from these elements useful for guiding the most effective treatment strategies and appropriate operational protocols.

Connect with a study center

  • European Institute of Oncology

    Milan,
    Italy

    Site Not Available

  • European Institute of Oncology

    Milan 3173435,
    Italy

    Active - Recruiting

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