Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis

Last updated: March 19, 2024
Sponsor: University of Split, School of Medicine
Overall Status: Active - Recruiting

Phase

N/A

Condition

Contact Dermatitis

Hives (Urticaria)

Dermatitis, Atopic

Treatment

niacinamide cosmetic product

placebo

Clinical Study ID

NCT06331390
2181-198-03-04-24-0008
  • Ages 18-50
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • young, healthy volunteers who gave written informed consent

Exclusion

Exclusion Criteria:

  • skin disease, skin damage on measurement sites, use of corticosteroids andimmunomodulators a month prior to the inclusion and during the trial, non-adherence tothe trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Study Design

Total Participants: 25
Treatment Group(s): 2
Primary Treatment: niacinamide cosmetic product
Phase:
Study Start date:
April 01, 2024
Estimated Completion Date:
July 31, 2024

Study Description

The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss

Connect with a study center

  • University of Split School of Medicine

    Split,
    Croatia

    Active - Recruiting

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