Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

Last updated: January 6, 2025
Sponsor: Tanta University
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

Bupivacaine

Dexmedetomidine

Ketamine

Clinical Study ID

NCT06331182
36264PR552/2/24
  • Ages > 18
  • All Genders

Study Summary

The aim of this study is to compare the role of dexmedetomidine and ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age ≥ 18 years.

  • Both sexes.

  • American Society of Anesthesiology (ASA) physical status I-III.

  • Scheduled for open thoracotomy.

Exclusion

Exclusion Criteria:

  • Patients with neurological or intellectual disability.

  • Infection at the injection site.

  • Opioid addiction.

  • Allergic reaction to local anesthetics.

  • Coagulation abnormalities.

  • Drug abuse.

  • Pregnancy.

  • Severe liver and/or renal failure.

  • Uncontrolled hypertension.

  • Severe cardiovascular problems.

  • Diabetes mellitus.

Study Design

Total Participants: 40
Treatment Group(s): 3
Primary Treatment: Bupivacaine
Phase:
Study Start date:
March 26, 2024
Estimated Completion Date:
November 01, 2024

Study Description

Postsurgical pain in patients who have undergone open thoracotomy for lung cancer or other lung surgeries is known to be very severe.

As a result, this pain alters spontaneous breathing, delays postoperative recovery, and persists as chronic post-thoracotomy pain syndrome . Post-thoracotomy pain syndrome is relatively common and is seen in approximately 50% of patients after thoracotomy. It is a chronic condition, and about 30% of patients might still experience pain 4 to 5 years after surgery.

Connect with a study center

  • Tanta University

    Tanta, ElGharbia 31527
    Egypt

    Site Not Available

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