Clinical Observation of Drug Retention Enema in Preventing Acute Radiation-induced Rectal Injury

Inclusion Criteria:

• There are clear indications for radiotherapy (pelvic radiotherapy or rectalradiotherapy) according to relevant guidelines;

• ECOG score 0-1;

• normal mind, clear consciousness;

• High compliance;

• Able to cooperate with the interviewer

Exclusion Criteria:

• Poor compliance, unwilling to participate or unable to cooperate with theinterviewer;

• Patients with other intestinal diseases (such as Crohn's disease, rectal ulcer, analfissure, anal fistula, hemorrhoids, etc.) and perianal diseases;

• serious heart, brain, liver, kidney disease;

• Long-term immune dysfunction;

• Pregnant or lactating women;

• Patients who terminate treatment for various reasons.