The Effect of a Ketone Drink on Blood Glucose Levels in People With Type 2 Diabetes

Last updated: April 15, 2025
Sponsor: University of Exeter
Overall Status: Completed

Phase

N/A

Condition

Diabetes Mellitus Types I And Ii

Diabetes And Hypertension

Diabetes Prevention

Treatment

Ketone supplement

Placebo supplement

Clinical Study ID

NCT06324669
4765060
  • Ages 41-70
  • All Genders

Study Summary

Ketones are naturally produced by our body and can affect our blood sugar levels. Ketones could be important in the treatment of type 2 diabetes (T2D). The purpose of this research is to determine if a ketone drink can lower blood sugar in people with T2D following a meal. This research will provide new knowledge about the regulation of blood sugar. This may also inform if ketone drinks could be used as a treatment for T2D.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Aged 41-70 years old

  2. Body mass index 27-40 mg/m²

  3. Type 2 diagnosis for more than 1 year

  4. HbA1c >6%

Exclusion

Exclusion Criteria:

  1. Currently following ketogenic diet

  2. Use of insulin

  3. HbA1c >10%

  4. Recent weight loss (>5kg in 6 months)

  5. Recent eGFR <30mL/min

  6. Heart failure

  7. Substance abuse

  8. Cancer

  9. Myocardial infarction within 6 months

  10. Pregnancy or consideration of

  11. Use of antipsychotic drugs

Study Design

Total Participants: 15
Treatment Group(s): 2
Primary Treatment: Ketone supplement
Phase:
Study Start date:
March 16, 2024
Estimated Completion Date:
January 26, 2025

Connect with a study center

  • Sport & Health Sciences University of Exeter

    Exeter, Devon EX1 2LU
    United Kingdom

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.