Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy (VERTEBRAL)

Last updated: June 10, 2025
Sponsor: Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cerebral Palsy

Treatment

N/A

Clinical Study ID

NCT06320288
IRR-FLAVIGNY-2023-1
  • Ages 18-18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

During the acquisition of posturokinetic abilities such as walking, postural control of the trunk is of paramount importance. Indeed, its development is strongly linked to the overall motor function of children. In cerebral palsy (CP), a term that refers to a set of motor disorders following a perinatal lesion, deficits in axial control are present from early childhood. These deficits are strongly correlated with the functional deficits observed in this population. In particular, during walking, deviations of the trunk (amplitudes, accelerations) are observed in the three planes of space. While recent literature increasingly questions the impact of trunk control deficit on the walking of children with CP, elements are still missing for a holistic understanding of the interaction between locomotor and postural disorders in children with CP. In particular, no study has focused on the deviations of trunk control and the center of mass (which is a global indicator of balance strategies) during the development and maturation of walking in children with CP. Therefore, the primary objective of this cross-sectional observational study will be to characterize the development of trunk control and center of mass during walking in children with CP.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Children (< 18 years) with cerebral palsy

  • GMFCS I to III

  • Independent walking with or without technical walking aids (walker, crutches, etc.)

  • Able to understand the instructions of various clinical assessments and functionalexplorations

  • Affiliated with a social security scheme

Exclusion

Exclusion Criteria:

Children with cerebral palsy

  • Neuro-orthopaedic surgery of the lower limbs or trunk within the last 12 months

  • Botulinum toxin A injections within the last 6 months

  • Therapeutic intervention targeting trunk control last 6 months

Typically developing children

  • Surgery on lower limbs or trunk last 12 months

  • Neurological and/or orthopedic pathology that may influence gait

Study Design

Total Participants: 270
Study Start date:
September 20, 2023
Estimated Completion Date:
September 30, 2028

Connect with a study center

  • Institut Régional de Médecine Physique et de Réadaptation

    Nancy, 54000
    France

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.