The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma

Last updated: December 6, 2024
Sponsor: Chinese PLA General Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

thyroid surgery

ultrasound-guided thermal ablation

Clinical Study ID

NCT06316895
S2023-706
  • Ages 18-80
  • All Genders

Study Summary

  1. To evaluate the clinical outcomes of ultrasound-guided thermal ablation and thyroid surgery for the treatment of papillary thyroid carcinoma;

  2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of papillary thyroid carcinoma;

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. patients age between 18 and 80 year old, both sex

  2. papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needleaspiration

  3. the largest diameter ≤2.0 cm

  4. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasisand distant metastasis on ultrasound, nech and chest CT

  5. follow-up period ≥12 months,

Exclusion

Exclusion Criteria:

  1. patients with convincing evidence of aggressive papillary thyroid carcinoma or othertype of thyroid cancer by biopsy

  2. history of neck radiation

  3. history of thyroid surgery

  4. coagulation disorder

  5. serious heart, respiratory, liver, or renal failure

  6. dysfunction of the vocal cord on the opposite side

Study Design

Total Participants: 3772
Treatment Group(s): 2
Primary Treatment: thyroid surgery
Phase:
Study Start date:
April 01, 2024
Estimated Completion Date:
December 31, 2029

Connect with a study center

  • Chinese PLA General Hospital

    Beijing,
    China

    Active - Recruiting

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