The Effect of Continuous Glucose Monitoring in Surgical Patients With Diabetes.

Last updated: November 27, 2025
Sponsor: Christian S. Meyhoff
Overall Status: Active - Recruiting

Phase

4

Condition

Diabetes And Hypertension

Diabetes Prevention

Treatment

Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7)

Clinical Study ID

NCT06314061
WARD-glucose RCT v.2.2
  • Ages > 18
  • All Genders

Study Summary

The goal of this randomised controlled trial to investigate the effect of continuous glucose monitoring (CGM) compared to standard point-of-care (POC) blood glucose measurements in surgical patients with diabetes in patients.

The main question it aims to answer is:

• Can the use of the CGM device Dexcom G7 with real-time alerts on dysglycaemia increase the time in range for glucose levels as compared with standard monitoring with point-of-care blood glucose in surgical patients with diabetes?

Participants will be asked to wear a CGM device (Dexcom G7, Dexcom Inc.) during their stay in the hospital. For patients in the intervention group, deviations of glucose levels will provide the nursing staff with alerts. All patients will receive standard care of their diabetes. The CGM device will be worn for up to 10 days or until discharge.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Medical history with diabetes mellitus (DM1 or DM2 (insulin-dependent andnon-insulin-dependent) requiring antidiabetic drug(s)

  • Acute or elective abdominal, orthopaedic, urological, or vascular surgery withestimated duration of surgery >45 minutes

  • Expected stay for at least one night in the hospital postoperatively

Exclusion

Exclusion Criteria:

  • Local skin symptoms including infection at the posterior aspect of the upper armthat does not allow the sensor to be placed on an unaffected skin area

  • Known allergy to the equipment plaster

  • Known pregnancy

  • Patients with pacemaker or implantable cardioverter defibrillator (ICD) device

  • Previous or currently scheduled for pancreatectomy (complete or partial)

  • Patients receiving hydroxyurea (these drugs may interfere with CGM readings)

Study Design

Total Participants: 200
Treatment Group(s): 1
Primary Treatment: Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7)
Phase: 4
Study Start date:
June 24, 2024
Estimated Completion Date:
June 01, 2026

Study Description

This is a prospective randomised controlled multicentre trial on patients living with diabetes who undergo surgery at Rigshospitalet, Copenhagen University, Bispebjerg and Frederiksberg Hospital, Copenhagen University, and Zealand University Hospital, Køge, Denmark

The study aims to investigate the effect of the CGM-device Dexcom G7 CGM in patients with diabetes undergoing surgery on the diabetic control. The Dexcom G7 provides glucose readings every 5 minutes and can send alerts on dysglycaemia (hypo- and hyperglycaemia) to mobile devices held by the nursing staff.

Patients will wear the CGM before, during and up to 10 days postoperatively.

The study will include 200 patients.

This study is part of an overall project that aims to investigate the use of CGM and continuous wireless monitoring of vital signs in patients with diabetes undergoing major surgery. Using this technology, postoperative complications including dysglycaemia can potentially be detected and treated earlier thus improving the perioperative care.

Connect with a study center

  • Department of Anaesthesiology and Intensive Care, Bispebjerg Hospital

    Copenhagen, The Capital Region Of Denmark 2400
    Denmark

    Site Not Available

  • Department of Anaesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet

    Copenhagen, The Capital Region of Denmark 2100
    Denmark

    Active - Recruiting

  • Department of Anaesthesiology and Intensive Care, Bispebjerg Hospital

    Copenhagen 2618425, The Capital Region of Denmark 2400
    Denmark

    Active - Recruiting

  • Department of Anaesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet

    Copenhagen 2618425, The Capital Region of Denmark 2100
    Denmark

    Active - Recruiting

  • Zealand University Hospital

    Køge, 4600
    Denmark

    Site Not Available

  • Zealand University Hospital

    Køge 2618415, 4600
    Denmark

    Active - Recruiting

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