National Register of Moderate and Severe Adult Atopic Dermatitis

Last updated: June 9, 2025
Sponsor: Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse
Overall Status: Active - Recruiting

Phase

N/A

Condition

Skin Infections/disorders

Rash

Hives (Urticaria)

Treatment

N/A

Clinical Study ID

NCT06313333
SID01
  • Ages > 18
  • All Genders

Study Summary

Collect clinical history and treatment data of AD in adulthood;

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Age 18 years

  2. Signature of informed consent

  3. Diagnosis of moderate and/or severe DA by a dermatologist specialist defined on thebasis of following criteria (10):

  • EASI 16

  • EASI <16 but with at least one of the following conditions:

  1. location in at least one of the following "critical" locations: face,hands, genitals
  2. QID > 10
  3. VAS itching > 7
  4. VAS sleep > 7

Exclusion

Exclusion Criteria:

  1. Patient unable to provide informed consent prior to any collection procedures dataon the study;

  2. unable to complete the procedures required for the study;

  3. a patient already participating in another follow-up register of the same disease.

Study Design

Total Participants: 1500
Study Start date:
June 15, 2020
Estimated Completion Date:
December 31, 2030

Study Description

Atopic dermatitis is a chronic-recurrent inflammatory skin disease with high prevalence in children and frequently presenting clinical remission during or after childhood; however, it may persist and/or recur, even after long and transient remission, adulthood. In addition, in some adult patients, DA is not present in pediatric age, but onset in adulthood: the investigators speak, in these cases, of adult-onset DA. The prevalence of DA is increasing all over the world and the cases in which clinical manifestations appear or persist during adolescence and/or adulthood are increased especially in industrialized countries. are not currently available specific laboratory markers for diagnosis of DA and, therefore, diagnosis is eminently clinical. In fact, at the present time, there are no validated diagnostic criteria, nor is there a clear consensus on diagnostic-therapeutic pathway to be followed when evaluating patients with adult DA. For these reasons, the collection of data related to various aspects of the DA such as those epidemiological, medical and clinical history, as well as the impact of the disease on the quality of life, results of crucial importance for estimating the real prevalence of this disease in Italy and also, possibly, to outline possible diagnostic criteria specific to adult DA, so that to facilitate and improve the diagnostic-therapeutic path of the patient. The intention of the project, therefore, is to create and use a National Register dedicated to DA patients in adulthood regardless of the period of onset of their pathology. aim to place the Italian Register as a supranational reference for international studies conducted on the adult DA.

Connect with a study center

  • ASST Spedali Civili di Brescia

    Brescia, 25123
    Italy

    Active - Recruiting

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