Retrospective and Prospective Observational Study in Patients With Advanced Basal Cell Carcinoma

Last updated: June 9, 2025
Sponsor: Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse
Overall Status: Active - Recruiting

Phase

N/A

Condition

Warts

Cancer/tumors

Carcinoma

Treatment

N/A

Clinical Study ID

NCT06309836
SID03
  • Ages > 18
  • All Genders

Study Summary

Retrospective and Prospective Observational Study in Patients With Advanced Basal Cell Carcinoma.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Male and female patients aged ≥ 18 years

  2. Patients diagnosed with advanced basal cell carcinoma of the skin, i.e. tumoursincluded in at least one of the following categories: locally advanced carcinoma (not radically treatable by surgery and/or radiotherapy), carcinoma with lymph nodeand/or distant metastatic localisation

  3. patients who have had at least one access (first visit or follow-up visit) at thedermatology or oncology outpatient clinic of the centres involved

  • Patients diagnosed with advanced BCC who have accessed the centre from 1January 2016 until the date of activation of the centre will be included in theretrospective cohort;

  • Patients diagnosed with advanced BCC who have accessed the centre from the dateof activation

  1. Signature of informed consent

Exclusion

Exclusion Criteria:

Patients incapable of giving informed consent

Study Design

Total Participants: 250
Study Start date:
June 23, 2021
Estimated Completion Date:
December 31, 2029

Study Description

Basal cell carcinoma (BCC) is an epithelial tumor characterized by the malignant proliferation of keratinocytes in the basal layer of the epidermis. It is part, along with squamous cell carcinoma (SCC),non-melanoma skin cancer (NMSC) and accounts for 80% of all skin cancers and the most common skin cancer in the United States and Europe. Estimates of BCC incidence, however, are inaccurate since in most countries there is no cancer register collecting data on BCC incidence and many patients are treated on a territorial outpatient basis, making data collection and epidemiological analysis complex. In recent decades, there has been an increasing trend in patients with BCC, as well as a reduction in the average age of onset, with a consequent drastic increase in the social and economic cost of healthcare facilities. From these considerations, arises the need to investigate and characterize the profile of patients with advanced BCC, the clinical characteristics and the course of such neoplasm, and the choice of therapeutic options available.

Connect with a study center

  • Irccs Fondazione Policlinico Gemelli

    Roma, ITA 00168
    Italy

    Active - Recruiting

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