A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser

Inclusion Criteria:

• Subjects must be able and willing to provide written informed consent and complywith the requirements of the study protocol;

• Subjects must be in good general health, based on answers provided during thescreening visit;

• Subjects must be able to read and understand English.

• Subjects must be above the age of 18.

• Subjects must have no history of skin conditions that affect the integrity of theskin barrier.

Exclusion Criteria:

• Are pregnant or lactating;

• Have a history of drug or alcohol abuse or have reported habitual alcohol intakegreater than 2 standard drinks per day [e.g., 2 beers, 2 glasses of wine, or 2 mixeddrinks];

• Are smoking or have a history of smoking;

• Presence of eczema, psoriasis, skin wounds or ulcers, or any other skin disease onthe thighs;

• Have birth marks, tattoos, scars, or any other disfiguration of the skin in the skinarea of interest;

• Presence of sunburn or tan in the treatment area;

• Use of any topical application of retinoids in the area of interest or systemicretinoids in the past 6 months;

• Use of any prescription topical medication, such as corticosteroids or hydroquinoneon the skin area of interest in the past 6 months;

• History of blood-clotting abnormality;

• History of keloid formation or hypertrophic scarring;

• History of allergic reaction to local anesthesia, aluminum chloride, and/orglycerol;

• Investigator, interfere with study evaluations or pose a risk to subject safetyduring the study;

• Exhibits any clinical conditions or takes any medication which in the opinion of theinvestigator may interfere with the study or pose a risk to subject safety duringthe study;

• Is not able to follow study protocol.