Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety

Inclusion Criteria:

1. Age 18-45 years old;

2. American society of Aneshesiologists（ASA）physical status classification system isgrade I-III;

3. Elective surgery is proposed

4. BMI of 19-30 kg/m2;

5. Patients who agreed to enroll in this study voluntarily

Exclusion Criteria:

1. Those who are known to be allergic to the drug ingredients in this study and theirallergic constitution;

2. Allergic history of general anesthesia drugs, opioid drugs, non-steroidal drugs;

3. History of neurological diseases; History of chronic pain; Drug and alcoholaddiction; A long history of opioid use; Opiates were given 48 hours before surgery

4. Coronary heart disease, bronchial asthma, severe hypertension, severe blood systemdysfunction, liver and kidney function, electrolyte abnormalities;

5. Respiratory insufficiency, respiratory failure;

6. BMI<18 kg/m2 or BMI>30kg/m2;

7. Poor compliance, unable to complete the experiment according to the study plan;Participants who have participated in clinical trials of other drugs within the last 4 weeks;

8. Preoperative Pittsburgh Sleep Quality Index (PSQI) higher than 7

9. Any circumstances deemed unsuitable for inclusion by the researcher for any reason.