Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

Inclusion Criteria:

• Age 18 or older

• Able to read and effectively communicate in English at the United States sites orable to read and effectively communicate in English or French at the Canadian site.

• Meets criteria for chronic insomnia

• Body Mass Index (BMI) 18.5 kg/m2 and higher

Exclusion Criteria:

• Age < 18

• Unable to read and effectively communicate in English at the United States sites orable to read and effectively communicate in English or French at the Canadian site.

• Unwilling to share email address/cell phone number to accept survey links.

• Life time diagnosis of psychotic or bipolar disorder

• Current use of supplemental oxygen for the treatment of sleep apnea

• History of severe apnea or an Apnea Hypopnea Index (AHI) ≥15 that is not currentlytreated with Positive Airway Pressure (PAP) therapy, an oral device or an implanteddevice, or was not treated with surgery or weight loss.

• Started new or changed treatment for sleep apnea in the past three months

• Does not meet criteria for chronic insomnia

• Meets criteria for narcolepsy or hypersomnia disorder

• Meets criteria for circadian rhythm disorder (including night shift work)

• Unstable medical conditions that would make participation unsafe or unfeasible

• Falls resulting in hospitalization, significant injury or fracture within past 12months

• 2 hospitalizations or emergency room visits within past 12 months for chronicconditions

• Active chemotherapy or radiation therapy for cancer

• Lifetime diagnoses/treatment of chronic renal failure, hepatic insufficiency,chronic heart failure

• Does not agree to refrain from other treatments for insomnia beyond what is offeredin this study

• BMI less than 18.5

• Substance abuse or dependence in the past 12 months

• Current use of prescription or over the counter medications taken for sleep greaterthan 2 times per week

• Current use of systemic corticosteroids or opiate medications

• Current pregnancy or breastfeeding; plans to get pregnant or unwillingness to usebirth control for the length of the study

• Current use of medications contraindicated with trazodone

• Sleep apnea or periodic leg movement disorder as determined by sleep study

• Blood Pressure levels defined as seated SBP greater than 180 or DBP greater than 110mmHg

• EKG corrected QT interval greater than or equal to 500 ms