Evaluate the Efficacy and Safety of D-2570 in Participants With Moderate-to-Severe Plaque Psoriasis

Inclusion Criteria:

1. Subject voluntarily takes part in the study after being fully informed,signs awritten ICF, and agrees to follow procedures specified in the study protocol;

2. Plaque psoriasis assessed by the investigator as suitable for systemic treatment andstable (defined as stable as no significant outbreak of morphological change ordisease activity assessed by the investigator) for at least 6 months prior tosigning informed consent;

3. During the screening period and before taking the investigational drug for the firsttime, psoriatic surface area (BSA) ≥10%, PGA score ≥ 3, PASI score ≥ 12;

4. Hematology, Blood chemistry and Urinalysis examination were basically normal.

Exclusion Criteria:

1. Erythrodermic psoriasis, pustular psoriasis, guttate psoriasis, reverse psoriasis,drug-induced psoriasis;

2. Have other skin lesions that affect the evaluation of treatment outcomes, such aseczema;

3. History of herpes zoster/herpes simplex, or presence of herpes zoster/herpes simplexinfection during the screening period;

4. Have a history of tuberculosis, or active tuberculosis, or latent tuberculosis, orsuspected clinical manifestations of tuberculosis infection;

5. Other conditions that the investigator considers inappropriate for participation inthe study.