Stellate Ganglion Block for Prevention of Post Mastectomy Depression

Last updated: February 15, 2026
Sponsor: Mansoura University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Mastectomy

Pain

Chronic Pain

Treatment

Stellate gangalion block

Clinical Study ID

NCT06263907
stellate ganglion block
  • Ages 21-65
  • Female

Study Summary

Complications after mastectomy include chronic pain and depression.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Female patients

  • Age ranging from 18 to 65 years

  • American Society of Anesthesiologists (ASA) no more than II

  • Had unilateral cancer breast

  • Scheduled to do unilateral modified radical mastectomy

Exclusion

Exclusion Criteria:

  • Pregnant female

  • Existing Horner syndrome

  • Had any neuromuscular disease

  • Had allergy to local anesthetics

  • History of use of analgesics

  • Had any deformity or a previous surgery in the neck or ipsilateral arm or breast

  • Had any contraindication to the procedure (coagulation disorders, local infection,sepsis)

  • Had any contraindication to the sympathetic blockade (decompensate cardiopulmonaryor hemodynamic disorders)

  • History of psychotic disorder including depression, bipolar disorder or personalitydisorder

  • Patient with Beck Depression Inventory (BDI) score more than 13

Study Design

Total Participants: 140
Treatment Group(s): 1
Primary Treatment: Stellate gangalion block
Phase:
Study Start date:
March 01, 2024
Estimated Completion Date:
December 30, 2028

Study Description

A mastectomy is surgery could be associated with complications include chronic pain and depression. In female breast cancer patients, the incidence of postoperative depression was 46.55%. Stellate ganglion block had been used for treating post-traumatic stress disorder (PTSD) and depression symptoms even in its prevention. Also, it used in treatment of chronic pain.

Connect with a study center

  • Maha

    Al Mansurah 360761,
    Egypt

    Active - Recruiting

  • Maha

    Mansoura,
    Egypt

    Site Not Available

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