Different Medications to Induce Labor

Last updated: March 27, 2026
Sponsor: Icahn School of Medicine at Mount Sinai
Overall Status: Active - Recruiting

Phase

3

Condition

Pregnancy

Treatment

Misoprostol

Pitocin

Pitocin only

Clinical Study ID

NCT06259097
STUDY-24-00118
  • Ages > 18
  • Female

Study Summary

This is a randomized controlled trial examining whether the use of misoprostol or pitocin, in combination with a foley catheter, is more effective at inducing labor in patients with a gravid BMI that is considered obese.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Pregnant patient presenting to labor & delivery for induction of labor with a BMI > = 30

Exclusion

Exclusion Criteria:

  • Pregnant patient presenting to labor & delivery for induction of labor with BMI < 30

Study Design

Total Participants: 300
Treatment Group(s): 4
Primary Treatment: Misoprostol
Phase: 3
Study Start date:
July 02, 2024
Estimated Completion Date:
June 30, 2026

Study Description

This randomized controlled trial will include patients with a BMI greater than 30 at the time of admission for their induction of labor. Patients will be randomized to either misoprostol or Pitocin to begin induction of labor, alongside the standard foley catheter, and the primary outcome of interest will be length of time from start of induction until delivery.

Connect with a study center

  • Bronx Care Health System

    Bronx, New York 10457
    United States

    Site Not Available

  • Mount Sinai Hospital

    New York, New York 10029
    United States

    Active - Recruiting

  • Bronx Care Health System

    The Bronx, New York 10457
    United States

    Active - Recruiting

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