Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard

Inclusion Criteria:

• Age 18 years or older;

• Patients with symptoms of myocardial ischemia such as angina pectoris, who have CAGshowing <70% stenosis at the most severe site or CTA showing non-severe stenosis

• Signed informed consent.

Exclusion Criteria:

• Patients with absolute or relative contraindications to SPECT-loaded myocardialperfusion, including acute myocardial infarction within 48 hours, significant leftmain coronary artery stenosis, bronchial asthma, and adenosine injection allergy;

• Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy,or moderate or severe valvular disease;

• Patients with Hemodynamic instability (systolic blood pressure<90 mmHg, or whorequires vasoactive drugs), or patients with tachyarrhythmia, Ⅱdegreeatrioventricular block and above that have not returned to normal;

• Patients who have severe renal abnormality with eGFR <30 ml/min, or patients who areon dialysis;

• Patients with malignant tumors with predicted survival of less than 1 year;

• Pregnant or breastfeeding women;

• Patients who are unable to enter the MCG device, who are unable to perform MCGexamination due to interference from metal implants or other reasons, or who aredeemed by the investigators to be unsuitable for enrollment.