Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.

Last updated: February 7, 2024
Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Overall Status: Active - Recruiting

Phase

2

Condition

Acne

Rash

Inflammatory Comedones

Treatment

Metformin and doxycycline

Clinical Study ID

NCT06252194
BSMMU/2022/11379
  • Ages > 18
  • All Genders

Study Summary

The goal of this clinical trial is to compare the effect of doxycycline and metformin in treatment of acne vulgaris patients. The main question is aimed to answer is whether metformin is more effective than doxycycline in treatment of acne vulgaris patient or not.

Patients will be asked to take doxycycline along with tropical treatment in one group and metformin along with tropical treatment in another group.

Researcher will compare the clinical improvement in two groups.

Eligibility Criteria

Inclusion

Inclusion Criteria: Newly diagnosed moderate and severe AV patients diagnosed by a dermatologist

Exclusion

Exclusion Criteria:

  • Patients receiving topical retinoids within last two months
  • Pregnancy and lactation
  • History of corticosteroids intake
  • Suffering from malignancy or any cosmetic induced acne

Study Design

Total Participants: 120
Treatment Group(s): 1
Primary Treatment: Metformin and doxycycline
Phase: 2
Study Start date:
March 05, 2023
Estimated Completion Date:
March 31, 2024

Connect with a study center

  • BSMMU

    Dhaka,
    Bangladesh

    Active - Recruiting

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