Association Between Postoperative Administration of L-Arginine and CSA-AKI

Last updated: April 2, 2025
Sponsor: Xijing Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Kidney Disease

Kidney Failure

Renal Failure

Treatment

L-Arginine hydrochloride

Clinical Study ID

NCT06248359
KY20232170-C-1
  • Ages > 18
  • All Genders

Study Summary

To investigate the association between the the early administration of L-Arginine after CPB-assisted cardiac surgery and the incidence of CS-AKI in adult patients. To test if it can reduce the incidence of post-operative AKI.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • adult patients (over 18 years)

  • underwent CPB assisted cardiac surgery

  • admitted to ICU

Exclusion

Exclusion Criteria:

  • congenital heart disease

  • underwent deep hypothermic circulatory arrest (DHCA)

  • with glomerular filtration rate (eGFR) below 30 mL/min/1.73 m²

Study Design

Total Participants: 7000
Treatment Group(s): 1
Primary Treatment: L-Arginine hydrochloride
Phase:
Study Start date:
December 01, 2023
Estimated Completion Date:
December 01, 2025

Connect with a study center

  • Xijing Hospital

    Xi'an, Shaanxi 710032
    China

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.