Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone

Phase

N/A

Condition

Dental Filling

Treatment

Cone-beam computed tomography systems (CBCT)

Sinus Lift augmentation

Clinical Study ID

NCT06247098

STUDY00004629

Ages > 18
All Genders

Study Summary

To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Patients of Tufts School of Dental Medicine (TUSDM)
Two stage sinus augmentations with <5mm (Zinner, Small 2004) residual bone height inneed of augmentation for implant placement
Full maxillary edentulism or Kennedy class I or III
18 to 100 year old

Exclusion

Exclusion Criteria:

Adults unable to consent (cognitively impaired adults)
Those who self-report as pregnant or breastfeeding
Wards of the state
Non-Viable neonates
Neonates of uncertain viability
< 18 years of age
Refusal to participate
Prior medical condition causing complications in bone metabolism
Osteoporosis
History of/or current chemotherapy
History of/or current head and neck radiation
Current heavy smoking > 10 cigarettes/day
Self-reported pregnancy or lactation
Previous history of sinus elevation procedure
Existing sinus pathology or pathology discovered at time of sinus augmentation orimplant placement
Absence of autogenous donor site

Study Design