Virtual Reality Based Vision Test in Patients With AMD

Last updated: February 1, 2024
Sponsor: Augenklinik Zurich West
Overall Status: Active - Recruiting

Phase

N/A

Condition

Aging

Geographic Atrophy

Macular Degeneration

Treatment

Virtual Reality (VR) Contrast Function Test

Clinical Study ID

NCT06241625
APL-GA-001
  • Ages 50-105
  • All Genders

Study Summary

To assess the usability, tolerability, and repeatability of the set of VR headset-based tasks.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Subjects ≥18 years of age diagnosed with AMD
  2. Subject Snellen BCVA score is 20/100 or better
  3. Ability to undergo quality optical coherence tomography (OCT) imaging
  4. Willing and able to give written informed consent

Exclusion

Exclusion Criteria:

  1. Unwilling to use headset
  2. Previous negative experience with a VR headset (eg, motion sickness, discomfort)
  3. Any known oculomotor impairment that would impact the ability of the subject toperform the tasks (eg, nystagmus, proptosis, apraxia of eyelid opening)
  4. Any manifest neurological or cognitive condition that would impair the subject'sunderstanding or performance on the test (eg, Alzheimer's disease, Parkinson'sdisease)
  5. Any physical limitations that would prohibit the use of the VR headset (eg, neckproblems)

Study Design

Total Participants: 50
Treatment Group(s): 1
Primary Treatment: Virtual Reality (VR) Contrast Function Test
Phase:
Study Start date:
October 20, 2022
Estimated Completion Date:
July 31, 2024

Study Description

In order to bridge the gap between the existing functional measures and AMD lesions, researchers are considering the use of VR tools.

This study is designed to assess the contrast sensitivity function mapping test (CSF radial sweep) in an elderly population with AMD.

The primary objective of this study is to assess the usability, tolerability, and repeatability of the set of VR headset-based tasks.

The secondary objective of this study is to assess the relationship between the metrics generated by VR-based functional tasks and the metrics derived from conventional clinical measurements of retinal anatomy and visual function.

The primary efficacy endpoint is the Contrast sensitivity function (CSF) area under curve (AUC) correlation to Snellen BCVA.

Connect with a study center

  • Augenklinik Zurich West

    Zürich, Zurich 8047
    Switzerland

    Active - Recruiting

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