Myasthenia Gravis Registry in China

Inclusion Criteria:

• Fluctuating weakness in skeletal muscles, such as extraocular, bulbar, limb muscles,etc.. Demonstrating fluctuation and fatigability: Weakness is usually worse in themorning and improves with rest; worsens with sustained activity.
• Patients themselves or their guardians can understand and sign the informed consentform. To meet the eligibility criteria, at least one of the following additional criteria must bemet:
• a. Positive Tensilon test;
• b. Decrease in compound muscle action potential by more than 10% with low-frequencyrepetitive nerve stimulation or widening of the "jitter" (the variability in time ofthe second action potential relative to the first) on single-fiber electromyography,with or without blocking;
• c. Positive antibodies: Serum testing positive for AChR antibodies, MuSK antibodies,or LRP4 antibodies.

Exclusion Criteria:

• Patients with mental illness who cannot cooperate.
• Patients with multiple organ dysfunction or in extremely critical condition, unable tocomplete relevant medical history collection or evaluation.