Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

Last updated: March 3, 2025
Sponsor: Shanghai 6th People's Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Cardiovascular Disease

Traumatic Brain Injury

Atherosclerosis

Treatment

Enhanced recovery after surgery

Conventional therapy

Clinical Study ID

NCT06241482
2024-179
  • Ages 18-75
  • All Genders

Study Summary

Enhanced recovery after surgery (ERAS) is a strategy of perioperative management aimed to accelerate the rehabilitation of patients through various optimized perioperative managements as well as ongoing adherence to a patient-focused, multidisciplinary, and multimodal approach. Alleviating the injury and stress caused by surgery or disease is the core principle of ERAS, which has been shown to reduce complication rates after surgery, promote patient recovery, decrease hospital length of stay and reduce costs. ERAS has been widely applied in many surgical perioperative fields, and it has achieved remarkable effects. However, there are few applications of ERAS in neurosurgery, especially in clinical trials of neurocritical care patients.

Therefore, the investigators attempt to conduct the study of ERAS in neurosurgical intensive patients using a series of optimized perioperative managements that have been verified to be effective by evidence-based medicine, and to evaluate the safety and effectiveness of ERAS in neurocritical care. The aim of this study is to explore the most suitable ERAS protocols to accelerate the postoperative rehabilitation process of neurocritical care patients, and to provide more evidence-based medicine for the effectiveness and safety of ERAS in neurosurgery.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18-75 years old

  • Patients with moderate or severe acute traumatic brain injury or cerebrovasculardisease requiring neurosurgical intensive care treatment

  • Hospitalization time ≥ 1 week

  • The guardian is able to understand and actively cooperate in completing the project

  • The guardian signs an informed consent form

Exclusion

Exclusion Criteria:

  • Patients undergoing non-surgical treatment

  • Patients diagnosed as brain death within the first 24 hours after admission to NICU

  • Patients undergoing cardiopulmonary resuscitation, maintenance dialysis, end-stagetumors, and disseminated cancer

  • Patients who withdraw treatment during hospitalization or are dischargedautomatically

  • Patients who underwent unplanned secondary surgery during the research process

  • Individuals who cannot be followed up during the research process

Study Design

Total Participants: 80
Treatment Group(s): 2
Primary Treatment: Enhanced recovery after surgery
Phase:
Study Start date:
October 15, 2024
Estimated Completion Date:
April 30, 2027

Connect with a study center

  • Shanghai 6th People's Hospital

    Shanghai, 200233
    China

    Active - Recruiting

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