Phase
Condition
Chest Pain
Dysrhythmia
Arrhythmia
Treatment
a dual energy catheter (RF and PFA) or PFA catheter only will be to treat PeAF,Cardiac Pulsed Electric Field Ablation Catheter
catheter ablation
Clinical Study ID
Ages 18-75 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Aged 18-75 years old;
Documented symptomatic persistent atrial fibrillation, defined as persistent atrialfibrillation lasting more than 7 days and less than 1 year;
Ineffective or intolerable after treatment with at least one Class I or Class IIIantiarrhythmic drug;
Fully understand the treatment protocol and voluntarily sign the informed consentform and be willing to undergo the tests, procedures and follow-ups required by theprotocol.
Exclusion
Exclusion Criteria:
Patients who have undergone left atrial surgery
Left atrial thrombosis
Patients with combined atrial tachycardia and atypical atrial flutter
Patients of childbearing age who are unable to use effective contraception duringthe 3-month period following enrollment
Anterior and posterior left atrial diameter ≥ 55mm
Left ventricular ejection fraction (LVEF) ≤ 40%
Previous atrial septal repair or atrial mucinous tumor
Active implants (e.g. pacemakers, ICDs, etc.) in the body
NYHA class III-IV cardiac function
Clear cerebrovascular disease within the last 6 months (including cerebralhemorrhage, stroke, transient ischemic attack)
Cardiovascular events within the last 3 months (including acute myocardialinfarction, coronary intervention or heart bypass surgery, prosthetic valvereplacement or repair, atrial or ventriculotomy)
Those with acute or severe systemic infections
Patients with severe liver or kidney disease, malignant tumors or end-stage diseasethat, in the opinion of the investigator, may interfere with the treatment,evaluation and compliance of this trial
Patients with significant bleeding tendency, hypercoagulable state and severehematologic disorders
Patients who have participated or are participating in other clinical trials within 3 months prior to enrollment
Patients who have other conditions that the investigator considers inappropriate forparticipation in this trial.
Study Design
Connect with a study center
West China Hospital of Sichuan University
Chengdu, Sichuan 610041
ChinaSite Not Available

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