Comparative Spectroscopic Analysis of Synovial Fluid From the Stable and Unstable Ankle

Last updated: April 2, 2025
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

Raman microspectroscopy

Clinical Study ID

NCT06228378
2022-A01300-43
  • Ages > 18
  • All Genders

Study Summary

A population of patients with chronic ankle instability for whom arthroscopic ligament stabilisation was indicated.

Main objective: to use the Raman microspectroscopy technique to characterise the synovial fluid of the unstable ankle in comparison with the synovial fluid of the healthy ankle.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients aged 18 or over who have signed their consent to participate in the study

  • Patients with chronic unilateral lateral ankle instability

  • Patients who have not responded to medical treatment and for whom arthroscopicstabilisation of the ankle is planned.

Exclusion

Exclusion Criteria:

  • Any history, anomaly or symptom relating to the contralateral ankle

  • Patient under court protection, guardianship or curatorship

Study Design

Total Participants: 25
Treatment Group(s): 1
Primary Treatment: Raman microspectroscopy
Phase:
Study Start date:
September 26, 2023
Estimated Completion Date:
January 28, 2025

Study Description

Single-centre, prospective, open-label study of patients undergoing ankle stabilisation surgery.

Patients will participate in the study for six months. Three arthrocentheses with synovial fluid sampling will be performed Two at D0: on the healthy ankle and the pathological ankle One at M6: on the operated ankle A follow-up visit will take place 10 days after the arthrocentesis performed at D0 and after the one performed at M6. The purpose of these visits, which are carried out systematically by the centre's doctors as part of the surgical procedures, is to check that there are no complications.

Connect with a study center

  • Clinique du Sport

    Paris, 75005
    France

    Site Not Available

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