Bilateral Two Levels Serratus Anterior Plane Block in Pediatric Cardiac Surgery With Median Sternotomy

Last updated: January 24, 2025
Sponsor: Cairo University
Overall Status: Active - Recruiting

Phase

1

Condition

Congenital Heart Disease

Pentalogy Of Cantrell

Heart Disease

Treatment

Bilateral two level serratus anterior block

Bilateral two level serratus anterior block

Control group

Clinical Study ID

NCT06221150
MD-341-2023
  • Ages 6-6
  • All Genders

Study Summary

The serratus anterior plane block (SAPB) is an anterolateral thoracic wall block that was described in 2013 by Blanco et al. who presented it as an alternative to other regional anesthetic techniques. It has been described in adults as an adjunct to general anesthesia or as a primary anesthetic technique for breast surgery, it has not been widely utilized as a primary anesthetic technique in the pediatric population. It was designed to block primarily the thoracic intercostal nerves and to provide complete analgesia of the lateral part of the thorax. It provides a viable alternative to paravertebral blockade and central neuraxial block in this patient population The investigators believe that the bilateral two-level injection technique may provide effective analgesia as its efficacy was not properly investigated in corrective heart surgeries with median sternotomy in the pediatric population.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Risk Adjustment for Congenital Heart Surgery (RACHS) category 1,2 and 3 Pediatricpatients undergoing corrective congenital cardiac surgeries via a median sternotomy

Exclusion

Exclusion Criteria:

  • • Refusal of legal guardian.

  • Patient with congestive heart failure .

  • Patient weaned from cardiopulmonary bypass on high doses of inotropic support (Adrenaline or noradrenaline more than 200ng/kg/min).

  • Patient undergoing Redo cardiac surgery.

  • Known allergy to local anesthetics.

  • Infection at injection site.

  • Bleeding disorders (drug induced i.e., coumadin; or genetic i.e. hemophilia; oracquired i.e. DIC), coagulopathy: PTT > 40 seconds, INR > 1.4, platelet count < 100x10⁹.

  • severe renal or hepatic insufficiency.

  • Neurological disorders because it will be difficult to assess their pain score (e.g. cerebral palsy).

Study Design

Total Participants: 48
Treatment Group(s): 3
Primary Treatment: Bilateral two level serratus anterior block
Phase: 1
Study Start date:
January 20, 2025
Estimated Completion Date:
June 30, 2025

Connect with a study center

  • Pediatric University Hospitals

    Cairo,
    Egypt

    Active - Recruiting

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