Comparison of Microneedling vs. Autologous Concentrated Growth Factor for the Treatment of Female Androgenetic Alopecia

Last updated: January 21, 2024
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Alopecia

Male Pattern Baldness

Hair Loss

Treatment

5% minoxidil

microneedling

Autologous Concentrated Growth Factor

Clinical Study ID

NCT06218394
20230984
  • Ages 18-65
  • Female

Study Summary

Microneedling and autologous concentrated growth factor (CGF) have established their potential effect in inducing hair regrowth. No study has compared the effect of microneedling and CGF in the treatment of female androgenetic alopecia (AGA).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. age between 18 and 65 years;；
  2. clinical diagnosis of female pattern hair loss；
  3. no previous laser treatments for AGA in the past six months before enrollment； 4)willingness to provide pictures and follow-up studies.

Exclusion

Exclusion Criteria:

  1. if presented with severe diseases of internal organs, eyes, or skin;
  2. inflammation, infection, or unhealed wounds on the skin around the site of treatmenton the head;
  3. systematic treatment with corticosteroids or other immunosuppressants andimmunomodulators in the past 3 months.

Study Design

Total Participants: 135
Treatment Group(s): 3
Primary Treatment: 5% minoxidil
Phase:
Study Start date:
December 14, 2023
Estimated Completion Date:
December 31, 2024

Study Description

Microneedling is a minimally invasive technique consisting of sterile microneedles for repetitive cutaneous puncturing that increase hair regrowth by growth factor release. Concentrated growth factor (CGF) is a form of platelet concentrate (PC) and concentrates higher levels of growth factors because of its varying programmed centrifugation process. Previous studies have showed that CGF injection in hairless scalp could enhance the hair density and optimize the hairless appearance in AGA patients. Both microneedling and CGF have established their potential effect in inducing hair regrowth. No study has compared the effect of microneedling and CGF in the treatment of female androgenetic alopecia.

Connect with a study center

  • Second Affiliated Hospital, School of Medicine, Zhejiang University, China

    Hangzhou, Zhejiang 310009
    China

    Active - Recruiting

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