Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases

Inclusion Criteria:

• Patients suffering from degenerative spinal pathology or spondylolisthesis whorequire instrumented stabilization on 1-2 levels;

• Age greater than or equal to 18 years;

• Ability to understand and sign the informed consent to the study and to follow therequired follow-ups.

Exclusion Criteria:

• Metabolic bone disease.

• History of Paget's disease or other osteodystrophies, whether acquired orcongenital, including renal osteodystrophy, hyperthyroidism, hypothyroidism,Ehlers-Danlos syndrome, osteogenesis imperfecta, achondroplasia.

• Neoplastic disease.

• History of mental disorder or current psychiatric treatment.

• Pregnancy.

• Immunodeficiency diseases.

• Infectious bone disease (discitis, osteomyelitis)

• Treatment with drugs that can interfere with bone metabolism

• Inability to understand and sign the informed consent to the study and to follow therequired follow-up visits.

• Alcohol and/or drug abuse

• Obesity

• Metal allergy

• Participation in other studies on drugs or devices (within 30 days)