Discover In-Hospital Cardiac Arrest

Last updated: November 12, 2024
Sponsor: Montefiore Medical Center
Overall Status: Completed

Phase

N/A

Condition

Heart Attack (Myocardial Infarction)

Circulation Disorders

Heart Failure

Treatment

N/A

Clinical Study ID

NCT06207201
2022-14602
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The Discover In-Hospital Cardiac Arrest (IHCA) study is a multicenter, prospective observational study aimed at better understanding variations in practice for the post-in-hospital cardiac arrest patient.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult (≥18 years old) patients

  • Patients with a cardiac arrest (a lack of palpable pulse or perfusing cardiacactivity) while admitted to the hospital

  • Patients admitted to a ward (telemetry or non-telemetry) or an intensive care unit,or are admitted but still in the emergency department waiting for a hospital bed

  • Patients who achieved return of spontaneous circulation (ROSC defined as >20 minutesof sustained spontaneous circulation) OR initiated on extracorporeal membraneoxygenation (eCPR) with chest compressions ongoing

  • Patients survived for 6 hours after ROSC

Exclusion

Exclusion Criteria:

  • Cardiac arrest in non-inpatients (e.g. outpatients, visitors)

  • Patients whose cardiopulmonary resuscitation (CPR) starts outside of the hospital

  • Non-index arrests (arrests that are not the patient's first arrest during thehospital admission; this also excludes patients who were initially admitted for anout-of-hospital cardiac arrest)

  • Patients suffering IHCA in the operating room (OR) or post anesthesia care unit (PACU)

  • Patients with cardiac arrest after arriving to an emergency department (ED) butprior to being evaluated and admitted to the hospital

  • Cardiac arrests lasting <2 minutes (i.e. chest compressions performed <2 minutes)

  • Cardiac arrests where the patient is transitioned to comfort focused care within 6hours of return of spontaneous circulation (ROSC)

Study Design

Total Participants: 1050
Study Start date:
October 16, 2023
Estimated Completion Date:
June 30, 2024

Study Description

There is considerable debate among experts concerning many components of intra- and post-arrest care. This study aims to increase the evidence base of these components, particularly temperature control, and prognostication in post-in-hospital cardiac arrest patients. In addition to providing insights regarding immediate and long-term post-arrest care, data collected will also be useful in studying variations in cardiopulmonary resuscitation practices.

This project is endorsed by the Society of Critical Care Medicine's (SCCM) Discovery, the Critical Care Research Network.

Connect with a study center

  • Montefiore Medical Center

    Bronx, New York 10467
    United States

    Site Not Available

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