Nutritional Study to Determine the Effect of Fish Oil on Atopic Dermatitis

Last updated: January 10, 2024
Sponsor: Møreforsking AS
Overall Status: Active - Recruiting

Phase

N/A

Condition

Atopic Dermatitis

Allergy

Rash

Treatment

LC-MUFA oil

Placebo

Clinical Study ID

NCT06194045
589440
  • Ages 18-80
  • All Genders

Study Summary

Atopic Dermatitis is associated with pronounced changes in the lipid composition in the skin. The lipid changes are influenced by and contributing to both the inflammatory circuit and the impaired barrier as well as changes in the skin microbiome This nutritional study will investigate the effect of long-chain monounsaturated fatty acid Cetoleic acid on atoptic dermatitis. Earlier studies have shown a anti-inflammatory effect of celoteic acid.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Women and men 18-80 years of age.
  • Diagnosed with active mild to moderate atopic dermatitis with an EASI of 1.1- 21.0.
  • Willing to refrain from oil supplements (omega-3, borage, evening primrose, etc.) for 1 month before study begin (washout) and during the study
  • Willing to take the study supplement for 6 months

Exclusion

Exclusion Criteria:

  • Known allergy to fish products
  • Subjects known to be pregnant or breast feeding
  • Subjects perceiving systemically administered medication for AD (other than topical)
  • Subjects with auto-immune diseases (except asthma and seasonal/perennial rhinitis)
  • Subjects with a diagnosis of other skin diseases

Study Design

Total Participants: 60
Treatment Group(s): 2
Primary Treatment: LC-MUFA oil
Phase:
Study Start date:
December 01, 2023
Estimated Completion Date:
October 10, 2024

Study Description

Women and men will be recruited to a placebo or a cetoleic-rich fish oil group and be examined for the effect on atopic dermatitis before, during and after the study period.

Connect with a study center

  • Helse Møre og Romsdal HF

    Ålesund, Møre Og Romsdal 6017
    Norway

    Active - Recruiting

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