Carbapenem Antibiotic Therapy for VIM Carbapenemase-Producing Enterobacteriaceae Infections

Last updated: December 14, 2023
Sponsor: University Hospital, Strasbourg, France
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

N/A

Clinical Study ID

NCT06185153
8779
  • Ages > 18
  • All Genders

Study Summary

Carbapenemase-producing Enterobacteriaceae (CPE) infections are emerging infections that pose a therapeutic challenge. These infections mainly occur in patients with prolonged hospitalization and repeated exposure to antibiotics. Certain strains, notably VIM-producing strains, may remain sensitive to carbapenems. CPE VIM strains are rare in France, but represent the main CPE strains in many countries. They are historically the main type of carbapenemases isolated at the Strasbourg University Hospital.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Adult patient (≥18)
  • Treated at the HUS for a VIM-producing enterobacteria infection between 01/01/2011 and 11/30/2022
  • Subjects who have not expressed their opposition to the reuse of their data forscientific research purposes.

Exclusion

Exclusion Criteria:

  • Patient having expressed his opposition to the retrospective reuse of his data forscientific research purposes.

Study Design

Total Participants: 70
Study Start date:
November 21, 2022
Estimated Completion Date:
December 31, 2023

Study Description

The circulation of multi-antibiotic-resistant bacterial strains is significant at the Strasbourg University Hospital and the investigators wish to report their local experience in the use of carbapenems in infections with enterobacteria producing carbapenemase type VIM.

Connect with a study center

  • Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France

    Strasbourg, 67091
    France

    Active - Recruiting

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